"The humanitarian crisis in Yemen remains the worst in the world," said the UN Office for the Coordination of Humanitarian Affairs in a statement.
"An estimated 80 percent of the population - 24 million - require some form of humanitarian or protection assistance, including 14.3 million who are in acute need.
"Severity of needs is deepening, with the number of people in acute need a staggering 27 percent higher than last year."
The OCHA statement said that two-thirds of the country was "already pre-famine", while one-third faces "acute vulnerabilities".
The war between the Huthis and pro-government troops escalated in March 2015, when President Abedrabbo Mansour Hadi fled into exile in Riyadh and a Saudi-led military coalition intervened against the rebels.
Since then, around 10,000 people - mostly civilians - have been killed and more than 60,000 wounded in the conflict, according to the World Health Organization.
Human rights groups say the real figure could be five times as high.