Egypt's blue-chip index fell 1.4 percent with 23 of its 30 stocks declining.
The country's biggest lender Commercial International Bank retreated 1.4 percent, while the top loser, Global Telecom, shed 6 percent, having lost nearly 5 percent in the last session after announcing its plan to convert outstanding shareholder loans of $370.6 million plus accrued interest into equity.
Heliopolis Co For Housing And Development dropped 2 percent in active trading. The company said its board approved the sale of its stake in Nasr Real Estate Development.
Saudi Arabia's index edged down 0.3 percent, with top petrochemical producer Saudi Basic Industries dropping 1.1 percent and Saudi British Bank losing 1.2 percent.
Saudi exchange data released on Sunday showed foreigners were net buyers of 1.03 billion riyals ($274.60 million) of stocks last week, up from the 134.3 million riyals of stocks foreigners bought the week before.
Insurance firms also fell as decliners outnumbered gainers by 28 to 5 stocks, with the index's biggest loser Saudi Enaya Cooperative Insurance slumping 7.1 percent.
But Riyad Bank added 0.7 percent. The company has picked Goldman Sachs to advise on its merger talks with National Commercial Bank (NCB), Reuters reported, citing sources familiar with the matter. NCB edged up 0.2 percent.
Dallah Healthcare gained 3.8 percent after the Capital Market Authority approved its request to increase capital through bonus shares.
The Abu Dhabi index gained for a fourth straight day, rising 0.6 percent. United Arab Emirates' largest lender First Abu Dhabi Bank increased 1.7 percent.
The bank said on Monday it had agreed to provide a 1.6 billion dirham ($436 million) loan to Abu Dhabi National Hotels for the acquisition of a number of Dubai-based hotels.
In Dubai, the index was down 0.4 percent as all but one of its real estate shares dropped.
The emirate's largest listed developer, Emaar Properties, slipped 2 percent, while DAMAC Properties lost 4 percent.
Qatar's index was up 0.2 percent with Middle East's largest lender Qatar National Bank gaining 0.8 percent and telecommunications firm Ooredoo adding 1.9 percent.
In Oman, the index edged up 0.1 percent, with Raysut Cement soaring 9.2 percent after reporting a higher annual revenue.