Giles, 31, took five for 81 as the tourists were bowled out for 267 chasing 478 for victory. That followed his first innings four for 129, giving the Warwickshire stalwart a match return of nine for 220.
And on Monday, Giles captured his 100th Test wicket when he bowled West Indies captain for 44 with a dream delivery that spun sharply through the gap between the master left-hander's bat and pad.
Vaughan, who in the course of the match became only the third batsman to make hundreds in both innings of a Lord's Test, paid tribute to his bowlers for dismissing the West Indies twice on a batsman-friendly surface. "I batted on that wicket. I realised how flat it was. I knew how hard it was going to be to get 20 wickets against a good West Indies batting line up," Vaughan told reporters after his team went 1-0 up in the four-match series.
"Full credit to Ashley Giles for putting them under pressure. He's proven over the last couple of years when he gets the conditions that warrant him he gets wickets.
"If you look at Giles's record he's played in 37 Tests and over half of them have been victories. You must be doing something right of that's the case. "He's still our most lethal spinning option."
Giles, who rediscovered his form with four for 46 in England's victorious third Test against New Zealand at Trent Bridge, last month, was understandably proud. His Monday return meant his name would be inscribed on the Lord's honours board in the players' dressing rooms that honour all those who have taken five wickets in an innings during a Lord's Test as well as score a hundred.